The QuickBooks Error 15222 message appears when users attempt to download software upgrades or payroll. Inappropriate internet settings, interference from antivirus software, or out-of-date digital signatures are typically the causes. To fix this issue, make sure security software isn't preventing QuickBooks updates, update digital signature certificates, and check internet options. Are you experiencing issues with QuickBooks? In order to chat with an expert, dial 1.855.738.2784.