Payroll or software upgrades are typically the cause of QuickBooks Error 15222 because of problems with internet settings, digital signature verification, or security software. It hinders the proper download of updates. Changing Internet Explorer, modifying firewall settings, and making sure digital signatures are set up correctly on your computer are all necessary to resolve this issue. Are you experiencing issues with QuickBooks? In order to chat with an expert, dial 1.855.738.2784.